Majors at the University of Connecticut

Biophysics

Biophysics is a branch of science concerned with the application of physical principles and methods to biological problems. At UConn the program of structural biology incorporates biophysics as well as cell biology and genetics. The study of biophysics applies math and physics in an attempt explain life processes. For example, biophysics deals with the function of organisms including how chlorophyll absorbs light through the process of photosynthesis, or how electrical impulses move throughout a nervous system. Biophysics research utilizes state of the art techniques and technology such as X-ray crystallography and transmission electron microscopes to determine molecular and macromolecular structure.

Those who choose to study biophysics can contribute valuable research that may lead to practical applications such as finding treatments to diseases ranging from influenza to cancer. The range of possibilities for those pursuing a career in biophysics continues to grow as more uses for its research become viable. Different areas of study include bioenergetics, biophysical theory and modeling, cell biophysics, channels, receptors, and transporters, electrophysiology, membranes, muscle and contractility, nucleic acids, photobiophysics, proteins, spectroscopy, imaging, and supramolecular assemblies.

Academic Department

• UConn's Department Molecular and Cell Biology

Nature of Work

Biophysicists focus mainly on research, but this research can vary greatly and include both basic and applied research. However, the essence of this research remains the same – biophysicists apply physics to biological problems. For example, one potential area of study for a biophysicist is chromosomal damage. This type of research includes following generations of cells that have been exposed to radiation to see if this damage makes the cells in future generations unstable. Research topics also range from studying the DNA in cells to developing a framework for understanding the function of living organisms. This can include the study of electrical impulses along the nerves; the study of brain functions; studying sight and hearing.

Sample Job Titles

Potential Employers

Potential employers of graduates with a degree in biophysics range from pure research institutions such as universities to publicly traded commercial drug companies such as Pfizer. Other institutions that engage in biophysics research include:

• Modeling and theory groups – Honig Lan at Columbia University
• Structural groups – Physiology and Biophysics at Mount Sinai
• Experimental groups – Drew Wooley’s Group at Toronto
• Bioinformatics groups – Wadsworth Center Labs in Albany, NY
• Structure prediction groups
• Protein design

Useful Skills

Skills that are an absolute necessity to be successful in the field of biophysics include a background in mathematics, physics, chemistry, and biology. However more intangible knowledge is also important for success, such as logical and critical thinking skills. One must also have a working knowledge of computers and the ability to solve problems. Having an interest in solving puzzles and a desire to figure out how things work are important qualities for individuals interested in biophysics.

Getting Experience

There are various ways to gain experience in biophysics. One may partake in a day of job shadowing, which involves spending the day ‘shadowing’ someone in the field of biophysics. It is a way to see first hand what the job is like and what it entails (such opportunities are available through the Department of Career Services). Another way to gain experience is to take part in a co-op or an internship. This allows students to work for a company in order to gain valuable real-world experience in the field.

Employment Opportunities

There is a wide range of employment opportunities for biophysics majors. Many biophysics majors continue their studies and eventually become faculty members at colleges, universities, and medical schools. These include both teaching and research positions in both public and private institutions. Many government institutions also hire biophysics majors such as Naval Research Laboratories, Departments of Agriculture and Defense, and the National Aeronautics and Space Administration. Furthermore, one may enter the commercial sector and apply his knowledge to finding new drugs and cures for diseases at any number of pharmaceutical companies.

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